- 14470
Unexplained Fatigue Panel
Specimen:
Collect
- Two SST
Also Acceptable:
- Two Red Top
Submit
- 5 mL (Min:3 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.
Special Handling
- Allow specimen to clot completely at room temperature
- Avoid Repeated Freeze/Thaw Cycles
- Minimize air exposure
- Separate from cells ASAP
If positive ANA Titer, the following EIA tests will be performed:
Centromere Antibody, Jo-1 Antibody, RNP Antibody, DNA Antibody, Scleroderma Antibody, Smith Antibody, Histone Antibody, Sjogren Antibodies A & B, Positive Anti-DNA confirmed with Crithidae. Additional charges will apply.
If the dsDNA Antibody is Positive, then the dsDNA AB Titer (Test# 2601) will be performed. Additional charges will apply.
Stability
Ambient: Unacceptable; Refrigerated: 2 Day(s); Frozen: 1 Month(s); Incubated: Unacceptable
Methodology
- See Individual Components
Performed
Mon-Fri
Reported
2-5 Day(s)
CPT Codes
- 83516x4
- 86038
- 86200
- 86235
- 86376
- 86431
- 86800
Interpretive Data
Please see report for interpretive data.
Reference Ranges for tTG IgG and IgA:
< 7.0 U/mL Negative
7.0 - 10.0 U/mL Equivocal
> 10.0 U/mL Positive
Reference Ranges for Gliadin IgG and IgA; B2 Glycoprotein IgA, IgG, and IgM:
< 7.0 U/mL Negative
7.0 - 10.0 U/mL Equivocal - Repeat testing in 4-6 weeks
> 10.0 U/mL Positive
Reference Ranges for Thyroglobulin (TG):
<280 IU/mL Negative
280-344 IU/mL Equivocal
>344 IU/mL Positive
Reference Ranges for TPO:
<60 IU/mL Negative
60-100 IU/mL Equivocal
>100 IU/mL Positive
Reference Ranges for dsDNA Ab:
Negative 0-200
Equivocal 201-300
Moderate Positive 301-800
Strong Positive >801
Reference Range for CCP3 Antibody:
<20 Units Negative
20-39 Units Weak Positive
40-59 Units Moderate Positive
>59 Units Strong Positive
Anti-cyclic citrullinated peptide (anti-CCP), IgG antibodies are present in 69-83 percent of patients with rheumatoid arthritis (RA) and have specificities of 93-95 percent. These autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.
The Anti-Nuclear Antibody test was performed by the indirect immunofluorescence technique using the Hep-2 substrate slides and the anti-Human IgG conjugate, fluorescein labeled.
Reference Ranges for tTG IgG and IgA:
< 7.0 U/mL Negative
7.0 - 10.0 U/mL Equivocal
> 10.0 U/mL Positive
Reference Ranges for Gliadin IgG and IgA; B2 Glycoprotein IgA, IgG, and IgM:
< 7.0 U/mL Negative
7.0 - 10.0 U/mL Equivocal - Repeat testing in 4-6 weeks
> 10.0 U/mL Positive
Reference Ranges for Thyroglobulin (TG):
<280 IU/mL Negative
280-344 IU/mL Equivocal
>344 IU/mL Positive
Reference Ranges for TPO:
<60 IU/mL Negative
60-100 IU/mL Equivocal
>100 IU/mL Positive
Reference Ranges for dsDNA Ab:
Negative 0-200
Equivocal 201-300
Moderate Positive 301-800
Strong Positive >801
Reference Range for CCP3 Antibody:
<20 Units Negative
20-39 Units Weak Positive
40-59 Units Moderate Positive
>59 Units Strong Positive
Anti-cyclic citrullinated peptide (anti-CCP), IgG antibodies are present in 69-83 percent of patients with rheumatoid arthritis (RA) and have specificities of 93-95 percent. These autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.
The Anti-Nuclear Antibody test was performed by the indirect immunofluorescence technique using the Hep-2 substrate slides and the anti-Human IgG conjugate, fluorescein labeled.
Components
- 2939 - CCP3 ANTIBODY IgG
- 2727 - TISSUE TRANSG.IgG
- 2752 - TISSUE TRANSG.IgA
- 2725 - GLIADIN (DGP)-IgA
- 2726 - GLIADIN (DGP)-IgG
- 1173 - dsDNA AB
- 2755 - ANTI-THYROGLOBIN
- 2754 - ANTI-T PEROXIDASE
- 2337 - RHEUMATOID FACTOR
- 2312 - ANA TITER
- 2301 - ANA PATTERN
- 2510 - ANA REFLEX
Last Updated: September 16, 2024 @ 9:13 am
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