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Laboratory Test Detail

Last Updated: December 9, 2023 @ 10:13 am

14470

Unexplained Fatigue Panel

Specimen:Collect:
  • Two SST

Also Acceptable:
  • Two Red Top
Submit:
  • 5 mL (Min:3 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.
Special Handling:
  • Allow specimen to clot completely at room temperature
  • Avoid Repeated Freeze/Thaw Cycles
  • Minimize air exposure
  • Separate from cells ASAP

  • If positive ANA Titer, the following EIA tests will be performed:
    Centromere Antibody, Jo-1 Antibody, RNP Antibody, DNA Antibody, Scleroderma Antibody, Smith Antibody, Histone Antibody, Sjogren Antibodies A & B, Positive Anti-DNA confirmed with Crithidae. Additional charges will apply.

    If the dsDNA Antibody is Positive, then the dsDNA AB Titer (Test# 2601) will be performed. Additional charges will apply.
Rejection Criteria:
  • Heat inactivated
  • Hemolyzed specimens
  • Lipemic Samples
  • Microbial Contamination
  • Particulate matter
Stability:Ambient: Unacceptable; Refrigerated: 2 Day(s); Frozen: 1 Month(s); Incubated: Unacceptable
Methodology:
  • See Individual Components
Performed:Mon-Fri
Reported:2-5 Day(s)
CPT Codes:
  • 83516x4
  • 86038
  • 86200
  • 86235
  • 86376
  • 86431
  • 86800
Interpretive Data:Please see report for interpretive data.

Reference Ranges for tTG IgG and IgA:
< 7.0 U/mL Negative
7.0 - 10.0 U/mL Equivocal
> 10.0 U/mL Positive

Reference Ranges for Gliadin IgG and IgA; B2 Glycoprotein IgA, IgG, and IgM:
< 7.0 U/mL Negative
7.0 - 10.0 U/mL Equivocal - Repeat testing in 4-6 weeks
> 10.0 U/mL Positive

Reference Ranges for Thyroglobulin (TG):
<280 IU/mL Negative
280-344 IU/mL Equivocal
>344 IU/mL Positive

Reference Ranges for TPO:
<60 IU/mL Negative
60-100 IU/mL Equivocal
>100 IU/mL Positive

Reference Ranges for dsDNA Ab:
<30 IU/mL Negative
30-75 IU/mL Equivocal
>75 IU/mL Positive


Reference Range for CCP3 Antibody:
<20 Units Negative
20-39 Units Weak Positive
40-59 Units Moderate Positive
>59 Units Strong Positive

Anti-cyclic citrullinated peptide (anti-CCP), IgG antibodies are present in 69-83 percent of patients with rheumatoid arthritis (RA) and have specificities of 93-95 percent. These autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.

The Anti-Nuclear Antibody test was performed by the indirect immunofluorescence technique using the Hep-2 substrate slides and the anti-Human IgG conjugate, fluorescein labeled.
Components:
  • 2939 - CCP3 ANTIBODY IgG
  • 2727 - TISSUE TRANSG.IgG
  • 2752 - TISSUE TRANSG.IgA
  • 2725 - GLIADIN (DGP)-IgA
  • 2726 - GLIADIN (DGP)-IgG
  • 2600 - dsDNA ANTIBODY
  • 2755 - ANTI-THYROGLOBIN
  • 2754 - ANTI-T PEROXIDASE
  • 2337 - RHEUMATOID FACTOR
  • 2312 - ANA TITER
  • 2301 - ANA PATTERN
  • 2510 - ANA REFLEX
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