Maternal Serum Screen, Alpha Fetoprotein

Specimen:

Collect

  • One SST

Also Acceptable:
  • One Red Top

Submit

  • 1 mL (Min:0.5 mL) Serum in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.

Also Acceptable:
  • 1 mL (Min:0.5 mL) Serum in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling

  • Avoid Repeated Freeze/Thaw Cycles
  • Separate serum from cells ASAP or within 2 hours of collection
  • Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation.

    Submit with Order:
    Patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient was diabetic at the time of conception, if there is a known family history of neural tube defects, if the patient is currently smoking, if the patient is taking valproic acid or carbamazepine (Tegretol), if this is a repeat sample, and the age of the egg donor if an in vitro fertilization.

Rejection Criteria

  • Hemolyzed specimens
  • Plasma

Stability

Ambient: 3 Day(s); Refrigerated: 2 Week(s); Frozen: 1 Year(s); Incubated: Unacceptable

Methodology

  • Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

3-4 Day(s)

CPT Codes

  • 82105

Interpretive Data

Please see report for interpretive data.

Components

  • 93241 - SPECIMEN
  • 93248 - Maternal Age
  • 93242 - DATING
  • 93202 - Est. Due Date
  • 93252 - Gestational Age
  • 93238 - Maternal Weight
  • 95045 - MAT DIAB AT CONC
  • 93244 - Family Hx of NTD
  • 93245 - Maternal Race
  • 93246 - Number of Fetuses
  • 93169 - Patients AFP
  • 93239 - MoM for AFP
  • 93240 - Interpretation
  • 92052 - SMOKING
Last Updated: July 26, 2026 @ 9:13 am

Disclaimer:

It is preferable to locate tests on the website and not rely on printed test information, which may soon be out of date.
Updated test information can only be guaranteed by using this website.

Choose the Right Test

ARUP Consult® assists with test selection and interpretation

How to Label Your Sample

  • Label Your Test 1
  • Label Your Test 2
  • Label Your Test 3
  • Label Your Test 4
  • Label Your Test 5

Common Test Phrases

  • Label Your Test 1
  • Label Your Test 2
  • Label Your Test 3
  • Label Your Test 4
  • Label Your Test 5

Common Lab Definitions

  • Serum 
  • Plasma 
  • STT