- 24 HR Urine Collection Preferred
- Keep Specimen Refrigerated During Collection
- State Collection Time
- State Volume
- Patients should consult their physician prior to stopping any medications but it is prefered to be off all medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to the test.
Foods and medications associated with altered urinary HIAA results:
Decreased HIAA: Aspirin, chlorpromazine (Thorazine), corticotropin, dihydroxyphenylacetic acid, ethanol, gentisic acid, homogentisic acid, hydrazine derivatives, imipramine (Tofranil®), isocarboxazid (Marplan), keto acids, levodopa, MAO inhibitors, methenamine, methyldopa (Aldomet®), perchlorperazine, phenothiazines (Compazine®), promazine, promethazine (Mepergan®).
Increased HIAA: Acetaminophen, acetanilide, caffeine, coumaric acid, diazepam (Valium®), ephedrine, fluorouracil, glycerol guaiacolate (Guaifenesin), melphalan (Alkeran®), mephenesin, methamphetamine (Desoxyn), methocarbamol (Robaxin®), naproxen, nicotine, phenacetin, phenmetrazine, phenobarbital, phentolamine, rauwolfia, reserpine.
Foods: Avocados, bananas, eggplant, pineapple, plums, tomatoes, walnuts.
Foods rich in serotonin and medications which may affect metabolism of serotonin must be avoided at least 72 hours before and during collection of urine for HIAA.