Laboratory Test Detail

Last Updated: June 18, 2024 @ 9:13 am


5-Hydroxyindoleacetic Acid (HIAA), Urine

  • Timed Urine in Timed Urine Container

Also Acceptable:
  • Random Urine in Sterile Specimen Container
  • 4 mL (Min:1 mL) Aliquot(s) Timed Urine in Sterile Specimen Container. Submit Refrigerated. Submit in a Standard Transport Tube.

Also Acceptable:
  • 4 mL (Min:1 mL) Random Urine in Sterile Specimen Container. Submit Refrigerated. Submit in a Standard Transport Tube.
Special Handling:
  • 24 HR Urine Collection Preferred
  • Keep Specimen Refrigerated During Collection
  • State Collection Time
  • State Volume
  • Patients should consult their physician prior to stopping any medications but it is prefered to be off all medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to the test.
    Foods and medications associated with altered urinary HIAA results:
    Decreased HIAA: Aspirin, chlorpromazine (Thorazine), corticotropin, dihydroxyphenylacetic acid, ethanol, gentisic acid, homogentisic acid, hydrazine derivatives, imipramine (Tofranil®), isocarboxazid (Marplan), keto acids, levodopa, MAO inhibitors, methenamine, methyldopa (Aldomet®), perchlorperazine, phenothiazines (Compazine®), promazine, promethazine (Mepergan®).
    Increased HIAA: Acetaminophen, acetanilide, caffeine, coumaric acid, diazepam (Valium®), ephedrine, fluorouracil, glycerol guaiacolate (Guaifenesin), melphalan (Alkeran®), mephenesin, methamphetamine (Desoxyn), methocarbamol (Robaxin®), naproxen, nicotine, phenacetin, phenmetrazine, phenobarbital, phentolamine, rauwolfia, reserpine.
    Foods: Avocados, bananas, eggplant, pineapple, plums, tomatoes, walnuts.
    Foods rich in serotonin and medications which may affect metabolism of serotonin must be avoided at least 72 hours before and during collection of urine for HIAA.
Rejection Criteria:
  • Any sample other than urine.
Stability:Ambient: Unacceptable; Refrigerated: 1 Week(s); Frozen: 2 Month(s); Incubated: Unacceptable
  • Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Reported:2-6 Day(s)
CPT Codes:
  • 83497
Interpretive Data:Please see report for interpretive data.
  • 93388 - URINE VOLUME
  • 93008 - CREAT, UR
  • 93009 - CREATININE
  • 93210 - 5-HIAA,URINE
  • 93211 - 5-HIAA, URINE
  • 93598 - 5-HIAA, URINE
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