Cardiolipin Antibodies, IgG / IgM

Specimen:

Collect

  • One SST

Also Acceptable:
  • One Green Top (Li Heparin)
  • One Lavender (EDTA)
  • One Pink Top (EDTA)
  • One Red Top

Submit

  • 1 mL (Min:0.5 mL) Serum in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.

Also Acceptable:
  • 1 mL (Min:0.5 mL) Serum in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.
  • 1 mL (Min:0.5 mL) Plasma in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.
  • 1 mL (Min:0.5 mL) Plasma in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.
  • 1 mL (Min:0.5 mL) Plasma in Standard Transport Tube. Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling

  • Allow specimen to clot completely at room temperature
  • Avoid Repeated Freeze/Thaw Cycles
  • If specimen is not tested within 2 days of collection, freeze serum.
  • Separate from cells ASAP

Rejection Criteria

  • Bacterially Contaminated Samples
  • Grossly Hemolyzed Samples
  • Grossly Lipemic Samples

Stability

Ambient: 8 Hour(s); Refrigerated: 14 Day(s); Frozen: 1 Month(s); Incubated: Unacceptable

Methodology

  • Chemiluminescent Immunoassay

Performed

Tuesday, Thursday

Reported

2-5 Day(s)

CPT Codes

  • 86147x2

Interpretive Data

Please see report for interpretive data.

Cardiolipin IgG and IgM Reference Range:
<10 U/mL Negative
10-40 U/mL Weak Positive
>40 U/mL Positive

Most patients with antiphospholipid antibody syndrome have moderate or high levels of cardiolipin antibodies and are positive for IgG only or IgG and IgM. (Br J Rheumatol 26:324-326, 1987).

Components

  • 2635 - CARDIOLIPIN, IgG
  • 2636 - CARDIOLIPIN, IgM
Last Updated: February 6, 2025 @ 10:13 am

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