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MPO/PR3 (ANCA) Antibodies

Specimen:

Collect

  • One SST

Also Acceptable:
  • One Red Top

Submit

  • 1 mL (Min:0.5 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling

  • Separate from cells ASAP

Stability

Ambient: 8 Hour(s); Refrigerated: 2 Day(s); Frozen: 1 Month(s); Incubated: Unacceptable

Methodology

  • Enzyme-Linked ImmunoSorbent Assay (ELISA)

Performed

Monday, Thursday

Reported

1-4 Day(s)

CPT Codes

  • 83520x2

Interpretive Data

Please see report for interpretive data.

Myeloperoxidase and Proteinase 3 Reference Ranges:
<21 Units Negative
21-30 Units Weak Positive
>30 Units Moderate to Strong Positive

ELISA method for ANCA correlates with Indirect Immunofluorescence as follows-
Myeloperoxidase = P-ANCA (Perinuclear Staining)
Proteinase 3 = C-ANCA (Cytoplasmic Staining)

Components

  • 2277 - MYELOPEROXIDASE
  • 2279 - PROTEINASE 3
Last Updated: October 13, 2024 @ 9:13 am

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT