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Laboratory Test Detail

Last Updated: December 5, 2023 @ 10:13 am

2224

Homocysteine

Specimen:Collect:
  • One Lavender (EDTA)

Also Acceptable:
  • One Green Top (Li Heparin)
  • One Pink Top (EDTA)
  • One Red Top
  • One SST
Submit:
  • 0.5 mL (Min:0.3 mL) Plasma . Submit Refrigerated. Submit in a Standard Transport Tube.

Also Acceptable:
  • 0.5 mL (Min:0.3 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.
Special Handling:
  • Allow specimen to clot completely ON ICE.
  • Avoid repeated freeze and thaw cycles.
  • Store specimen on ice between collecting and centrifugation. Samples may be kept on ice for up to 6 hours prior to separation by centrifugation.

    Avoid air exposure longer than 3 hours.

    **Due to instability of specimen, homocysteine cannot be added to previously drawn specimens**
Rejection Criteria:
  • Grossly Hemolyzed Samples
  • Heat inactivated
  • Lipemic Samples
  • Microbial Contamination
  • Specimen submitted at room temperature
  • Specimens containing particulate matter (Fibrin, RBC, or other matter)
Stability:Ambient: Unacceptable; Refrigerated: 2 Week(s); Frozen: 8 Month(s); Incubated: Unacceptable
Methodology:
  • Enzymatic Conversion
  • Reduction
Performed:Sunday, Mon-Fri
Reported:1-3 Day(s)
CPT Codes:
  • 83090
Interpretive Data:General Reference Range : 5-20 umol/L
Male Reference Ranges
  • 0 - 60 year(s) : 5-15 umol/L
  • 60 - 150 year(s) : 5-20 umol/L

Female Reference Ranges
  • 0 - 60 year(s) : 5-15 umol/L
  • 60 - 150 year(s) : 5-20 umol/L


Specimens from patients who are on drug therapy involving S-adenosyl-methionine may show falsely elevated levels of homocysteine. Patients who are taking methotrexate, carbamazepine, phenytoin, nitrous oxide, anticonvulsants, or 6-azauride triacetate may have elevated levels of homocysteine due to their affect on the pathway.

Reference range changed as of 11/16/2020
Components:
  • 2224 - HOMOCYSTEINE
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