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Valproic Acid

Specimen:

Collect

  • One Red Top

Also Acceptable:
  • One Blue Top (Na Citrate)
  • One Gray Top
  • One Green Top (Li Heparin)
  • One Green Top (Na Heparin)
  • Four Lavender (EDTA)
  • One Pink Top (EDTA)
  • One SST

Submit

  • 1 mL (Min:0.5 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.

Also Acceptable:
  • 1 mL (Min:0.5 mL) Plasma . Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling

  • Allow specimen to clot completely at room temperature
  • Avoid Repeated Freeze/Thaw Cycles
  • Separate from cells ASAP
  • State Patient's Last Dose
  • For trough level specimens should be collected just before next scheduled dose. Peak is 1-3 hours after oral dose.
    SST ONLY STABLE UP TO 24 HOURS.
    State patient's last dose in hours.

Stability

Ambient: 2 Hour(s); Refrigerated: 2 Day(s); Frozen: 12 Month(s); Incubated: Unacceptable

Methodology

  • Immunoassay

Performed

Mon-Fri

Reported

1-3 Day(s)

CPT Codes

  • 80164

Interpretive Data

Please see report for interpretive data.
Valproic acid serum concentrations of 50 - 100 µg/mL effectively control generalized and partial seizures in most patients.

Seizure control may improve at levels greater than 100 µg/mL, but toxicity may occur at levels of 100 - 150 µg/mL.

Components

  • 2711 - VALPROIC ACID
  • 2911 - LAST DOSE
Last Updated: October 23, 2024 @ 9:13 am

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Common Lab Definitions

  • Serum 
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  • STT