Autoimmune Panel

Specimen:

Collect

  • Two SST

Also Acceptable:
  • Two Red Top

Submit

  • 2 mL (Min:1 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling

  • Allow specimen to clot completely at room temperature
  • Avoid Repeated Freeze/Thaw Cycles
  • Separate from cells ASAP
  • If the dsDNA Antibody is Positive, then the dsDNA AB Titer (Test# 2601) will be performed. Additional charges will apply.

Rejection Criteria

  • Grossly Hemolyzed Samples
  • Heat inactivated
  • Lipemic Samples
  • Microbial Contamination
  • Particulate matter

Stability

See Individual Components

Methodology

  • See Individual Components

Performed

Monday, Wednesday, Thursday

Reported

2-3 Day(s)
Positive ANA Results will be titered and reported next day.
Positive Anti DNA is confirmed with Crithidae.

CPT Codes

  • 83516
  • 86038
  • 86140
  • 86160x2
  • 86235x8
  • 86431

Interpretive Data

Please see report for interpretive data.

Histone Ab Reference Range:
<1.0 Units Negative
1.0-1.5 Units Weak Positive
1.6-2.5 Units Moderate Positive
>2.5 Units Strong Positive

Sm/RNP Ab Reference Range:
<20 Units Negative
20-39 Units Weak Positive
40-80 Units Moderate Positive
>80 Units Strong Positive

dsDNA Ab Reference Range:
Negative 0-200
Equivocal 201-300
Moderate Positive 301-800
Strong Positive >801

Sjogrens A/B Ab, Smith Ab, Jo-1 Ab, and Scleroderma Ab Reference Ranges:
<20 Units Negative
20-39 Units Weak Positive
40-80 Units Moderate Positive
>80 Units Strong Positive

Centromere Ab Reference Range:
<20 Units Negative
20-30 Units Weak Positive
>30 Units Moderate to Strong Positive

The Anti-Nuclear Antibody test was performed by the indirect immunofluorescence technique using the Hep-2 substrate slides and the anti-Human IgG conjugate, fluorescein labeled.

Components

  • 2312 - ANA TITER
  • 2301 - ANA PATTERN
  • 1173 - dsDNA AB
  • 2366 - SMITH AB
  • 2365 - SM/RNP AB
  • 2367 - SJOGRENS A AB
  • 2368 - SJOGRENS B AB
  • 2331 - CENTROMERE AB
  • 2369 - SCLERODERMA AB
  • 2337 - RHEUMATOID FACTOR
  • 2320 - C-REACTIVE PROT
  • 2356 - COMPLEMENT C3
  • 2357 - COMPLEMENT C4
  • 2393 - JO-1 AB
  • 2399 - HISTONE AB
Last Updated: February 6, 2025 @ 10:13 am

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Common Lab Definitions

  • Serum 
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