Laboratory Test Detail

Last Updated: March 22, 2019 @ 9:13 am

1443

Autoimmune Panel

Specimen:Collect:
  • One SST

Also Acceptable:
  • One Red Top
Submit:
  • 2 mL (Min:1 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.
Special Handling:
  • Allow specimen to clot completely at room temperature
  • Avoid Repeated Freeze/Thaw Cycles
  • Separate from cells ASAP
  • If the dsDNA Antibody is Positive, then the dsDNA AB Titer (Test# 2601) will be performed. Additional charges will apply.
Rejection Criteria:
  • Grossly Hemolyzed Samples
  • Heat inactivated
  • Lipemic Samples
  • Microbial Contamination
  • Particulate matter
Stability:See Individual Components
Methodology:
  • See Individual Components
Performed:Monday, Wednesday, Thursday
Reported:2-3 Day(s)
Positive ANA Results will be titered and reported next day.
Positive Anti DNA is confirmed with Crithidae.
CPT Codes:
  • 83516
  • 86038
  • 86140
  • 86160x2
  • 86235x8
  • 86431
Interpretive Data:Please see report for interpretive data.

Histone Ab Reference Range:
<1.0 Units Negative
1.0-1.5 Units Weak Positive
1.6-2.5 Units Moderate Positive
>2.5 Units Strong Positive

Sm/RNP Ab Reference Range:
<20 Units Negative
20-39 Units Weak Positive
40-80 Units Moderate Positive
>80 Units Strong Positive
A positive Sm/RNP Ab result indicates the presence of antibodies reactive with the Smith (Sm) protein and/or ribonuclear protein (RNP). This Sm/RNP assay cannot distinguish between Anti-Sm and Anti-RNP activity, thus should be considered with the Sm Ab test result to determine clinical significance.

dsDNA Ab Reference Range:
<30 IU/ml Negative
30-75 IU/mL Equivocal
>75 IU/mL Positive

Sjogrens A/B Ab, Smith Ab, Jo-1 Ab, and Scleroderma Ab Reference Ranges:
<20 Units Negative
20-39 Units Weak Positive
40-80 Units Moderate Positive
>80 Units Strong Positive

Centromere Ab Reference Range:
<20 Units Negative
20-30 Units Weak Positive
>30 Units Moderate to Strong Positive

PLEASE NOTE REFERENCE RANGE CHANGES: Sm/RNP Ab as of 07/11/2017. dsDNA as of 07/17/2017. Centromere Ab, Histone Ab, JO-1 Ab, Scleroderma Ab, Sjogrens A/B Ab, and Smith Ab as of 7/24/2017.
Components:
  • 2312 - ANA TITER
  • 2301 - ANA PATTERN
  • 2600 - dsDNA ANTIBODY
  • 2366 - SMITH AB
  • 2365 - SM/RNP AB
  • 2367 - SJOGRENS A AB
  • 2368 - SJOGRENS B AB
  • 2331 - CENTROMERE AB
  • 2369 - SCLERODERMA AB
  • 2337 - RHEUMATOID FACTOR
  • 2320 - C-REACTIVE PROT
  • 2356 - COMPLEMENT C3
  • 2357 - COMPLEMENT C4
  • 2393 - JO-1 AB
  • 2399 - HISTONE AB
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