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Factor V Leiden

Specimen:

Collect

  • One Lavender (EDTA)

Also Acceptable:
  • One Pink Top (EDTA)

Submit

  • 4 mL (Min:2 mL) Whole blood in Lavender (EDTA). Submit Refrigerated.

Also Acceptable:
  • 6 mL (Min:2 mL) Whole blood in Pink Top (EDTA). Submit Refrigerated.

Special Handling

  • Variant analyzed: c.1601G>A (p.Arg534Gln), referred to as Factor V Leiden.

Stability

Ambient: Unacceptable; Refrigerated: 1 Month(s); Frozen: Unacceptable; Incubated: Unacceptable

Methodology

  • Mass Spectrometry Coupled with End-Point PCR

Performed

Wednesday

Reported

1-7 Day(s)

CPT Codes

  • 81241

Interpretive Data

General Reference Range : negative

Where appropriate, medical consultation and/or genetic counseling should be offered to patients to inform and explain the risk implications and genetic implications of these test results.
Patient DNA is assayed for the Factor V Leiden G1691A mutation by polymerase chain reaction (PCR) and MOLDI-TOF mass spectrometry technology. The product of PCR is detected on the Agena Bioscience MassARRAY system.
Other causes of activated protein C resistance and hereditary forms of venous thrombosis are not ruled out. The test result must be interpreted along with the patient's clinical history and other pertinent laboratory data.
Variant analyzed: c.1601G>A (p.Arg534Gln), referred to as Factor V Leiden.
Laboratory Developed Test (LDT). This test was developed and its performance characteristics determined by Interpath Laboratory in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Components

  • 1152 - FACTOR V LEIDEN
Last Updated: October 7, 2024 @ 9:13 am

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