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Treponema pallidum (Syphilis) Screening Cascade

Specimen:

Collect

  • One SST

Also Acceptable:
  • One Red Top

Submit

  • 1 mL (Min:0.5 mL) Serum . Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling

  • Separate from cells ASAP
  • If Treponemal Antibody Total is Reactive then the RPR (Test# 1033) will be performed. If the RPR is Reactive, then the RPR Quant (Test# 2005) will be performed. If the RPR is Non-Reactive then the Treponemal Ab, IgG (Test# 2628) will be performed. Additional charges will apply.

Stability

Ambient: Unacceptable; Refrigerated: 1 Week(s); Frozen: 1 Month(s); Incubated: Unacceptable

Methodology

  • Chemiluminescent Immunoassay

Performed

Mon-Fri

Reported

1-3 Day(s)

CPT Codes

  • 86780

Interpretive Data

General Reference Range : non-reactive
When the TREPONEMAL AB TOT test is reactive, it will reflex to RPR. If the RPR is non-reactive, it will then reflex to the TREPONEMAL AB IgG test for confirmation. When interpreting these results, consider the patient's history of prior infections and treatment and the patient's risk of re-infection. If diagnosis is still unclear, recommend re-testing in 2-4 weeks.

Components

  • 1003 - TREPONEMAL AB TOT
Last Updated: October 10, 2024 @ 9:13 am

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Common Lab Definitions

  • Serum 
  • Plasma 
  • STT