91023      APC Resistance
Specimen:
  Collect: One 4 mL Blue Top (Na Citrate)  
  Submit: 1.5 mL (Min:1 mL) Plasma. Submit Frozen. Submit in a Standard Transport Tube.  
  Rejection Criteria: Hemolyzed specimens 
  Stability: Ambient: 4 Hour(s); Refrigerated: 4 Hour(s); Frozen: 2 Week(s); Incubated: Unacceptable 
Performed: Monday, Wednesday, Friday 
Reported: 2-5 Day(s) 
CPT Codes:
85307 - Activated Protein C (APC) Resistance Assay
Interpretive Data:
General Reference Range : >0.61

Ratios less than or equal to 0.83 suggest APC resistance. This method uses Factor V deficient plasma; therefore, APC resistance due to a nonfactor V mutation will not be detected.