91005 5-Hydroxyindoleacetic Acid (HIAA), Urine

Specimen:

Collect:

Timed Urine

Also Acceptable
Random Urine

Submit:

4 mL (Min:1 mL) Aliquot(s) Timed Urine. Submit Refrigerated. Submit in a Standard Transport Tube.

Also Acceptable
5 mL (Min:3 mL) Random Urine. Submit Refrigerated. Submit in a Standard Transport Tube.
4 mL (Min:1 mL) Random Urine. Submit Refrigerated. Submit in a Standard Transport Tube.

Special Handling:

24 HR Urine Collection Preferred
Keep Specimen Refrigerated During Collection
State Collection Time
State Volume
Patients should consult their physician prior to stopping any medications but it is prefered to be off all medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to the test.
Foods and medications associated with altered urinary HIAA results:
Decreased HIAA: Aspirin, chlorpromazine (Thorazine), corticotropin, dihydroxyphenylacetic acid, ethanol, gentisic acid, homogentisic acid, hydrazine derivatives, imipramine (Tofranil®), isocarboxazid (Marplan), keto acids, levodopa, MAO inhibitors, methenamine, methyldopa (Aldomet®), perchlorperazine, phenothiazines (Compazine®), promazine, promethazine (Mepergan®).
Increased HIAA: Acetaminophen, acetanilide, caffeine, coumaric acid, diazepam (Valium®), ephedrine, fluorouracil, glycerol guaiacolate (Guaifenesin), melphalan (Alkeran®), mephenesin, methamphetamine (Desoxyn), methocarbamol (Robaxin®), naproxen, nicotine, phenacetin, phenmetrazine, phenobarbital, phentolamine, rauwolfia, reserpine.
Foods: Avocados, bananas, eggplant, pineapple, plums, tomatoes, walnuts.
Foods rich in serotonin and medications which may affect metabolism of serotonin must be avoided at least 72 hours before and during collection of urine for HIAA.

Stability:

Ambient: Unacceptable; Refrigerated: 1 Week(s); Frozen: 2 Week(s); Incubated: Unacceptable

Methodology:

High performance liquid chromatography (HPLC)

Performed:

Tuesday, Wednesday, Thursday, Friday, Saturday, Sunday

Reported:

2-4 Day(s)

CPT Codes:

83497

Interpretive Data:

Please see report for interpretive data.

Components:

93008 - CREAT, UR	93009 - CREAT, UR
93200 - INTERPRETATION	93210 - 5-HIAA,URINE
93211 - 5-HIAA, URINE	93598 - 5-HIAA, URINE