2091      Leukocyte Alkaline Phosphatase
Specimen:
  Collect: One 4 mL Green Top (Li Heparin)  
  Submit: One 4 mL Green Top (Li Hep). Submit Refrigerated.  
  Special Handling: Protect from Light
Must arrive at Laboratory within 8 hours for testing.
Call Laboratory to notify that sample is coming. 
  Stability: Ambient: Unacceptable; Refrigerated: 8 Hour(s); Frozen: Unacceptable; Incubated: Unacceptable 
Methodology: Microscopy 
Performed: Mon-Fri 
Reported: 1-3 Day(s) 
CPT Codes:
85540 - Leukocyte Alk Phos
Interpretive Data:
General Reference Range : 32-182

LAP is LOW in chronic myelogenous leukemia, 50% of acute leukemias, paroxysmal nocturnal hemoglobinuria, erythroleukemia, collagen-vascular diseases, early infectious mononucleosis and in hereditary hypophasphatasia.
LAP is elevated in neutrophilia due to stress and infections, myeloproliferative disorders, pregnancy, oral contraceptives, acute lymphocytic leukemia, and Hodgkin's disease.